The COVID-19 pandemic has significantly reshaped the global business landscape, forcing organizations to rapidly adapt to remote work, digital transformation, and increased reliance on technology. As the world continues to navigate the long-term impacts of the pandemic, Chief Information Security Officers (CISOs) face a critical responsibility to safeguard their organizations against evolving cybersecurity threats. This article explores the ongoing cybersecurity challenges stemming from COVID-19 and provides practical insights for CISOs to prepare for and mitigate potential risks. We will examine the key impacts of the pandemic on cybersecurity, discuss strategies to strengthen resilience, and highlight the importance of long-term preparedness.